Please take a moment and listen to the introductory video on your left. Then, view the video below and follow the instructions for the quiz.

The video below from the Psychedelic Science in the 21st Century is available for continuing education credit through the co-sponsorhip of the Mulitdisciplinary Association for Psychedelic Studies and the Spiritual Competency Resource Center for many physicians, psychologists, social workers, MFTs, nurses and other healthcare professionals.


    1. Watch the video on your left. There is no charge for viewing the video
    2. Answer the questions below.
    3. When finished, press the Score My Quiz button. After that you will have an option to checkout and print your CE certificate.*
    4. To view CE information click here

David Nichols, Ph.D. Advances In Understanding How Psychedelics Work In The Brain

Course Presenter(s):
Author(s): David Nichols, Ph.D. | (click author name for biography)

Course Description: This talk presents an overview of what psychedelics are, and several significant events in this field in the past four decades. A comparison is explored between molecular structures, and how they were related to the structure of the neurotransmitter serotonin. The receptors that have been identified as targets for psychedelics are discussed, and their brain localization noted, followed by a brief description of where the receptors are located, and what happens inside the cell after the receptor is activated by a psychedelic. Particular note is made of the difficulty in identifying psychedelic molecules in the absence of human experimentation, which is illegal.
Biography of Presenter:
David Nichols, Ph.D., holds the Robert C. and Charlotte P. Anderson Distinguished Chair in Pharmacology at the Purdue University College of Pharmacy, and is an Adjunct Professor of Pharmacology and Toxicology at Indiana University School of Medicine. He received a B.S. in chemistry from the University of Cincinnati in 1969, and a Ph.D. in Medicinal Chemistry from the University of Iowa in 1973, followed by postdoctoral work in pharmacology at the University of Iowa College of Medicine. He joined Purdue as an Assistant Professor in 1974, rising through the ranks to become Associate and then Full Professor. He was named the 2004 Irwin Page Lecturer by the International Serotonin Club and in 2006 received the first Provost’s Outstanding Graduate Mentor award from Purdue University. He has published nearly 300 scientific articles, most of which deal with the relationship between molecular structure and biological action. Professor Nichols is unusual in that his research encompasses a breadth of expertise held by few others. He has been continuously funded by the NIH for nearly three decades and has served on numerous government review panels. He is recognized by most scientists as one of the world’s leading authorities on the chemistry and pharmacology of psychedelics. Recently, he has been developing in silico-activated G protein-coupled receptor models to understand how drugs activate their receptors.

Date of original release: April 18, 2010
Termination date (date after which enduring material is no longer certified for credit): April 17, 2012

David Nichols, Ph.D. - Advances In Understanding How Psychedelics Work In The Brain from MAPS: Psychedelic Science on Vimeo.

True/False Comprehension Quiz

The three chemical types of Hallucinogen Molecules are Phenethylamines, Trptamines and Lysergamides.
Psychedelics enhances the burst fire and length at which the locus coeruleus fires for things that normally would not produce “novelty”.
Psychedelics cause raphe cells to start firing actively like in REM sleep.
Today, it is well understood what makes LSD so potent.
There is no molecular similarity between serotonin and psilocin (which is one of the tryptamines).
Psychedelics are partial to full agonists some of acting similarly to serotonin.
According to Nichols antidepressants such as Prozac and migraine medications would not have been able to be developed if it weren’t for the discovery of LSD.
Nichols believe that LSD may form a metabolite for some people.

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